Why did this rash persist and worsen despite treatment?Īnswer: The patient has tinea faciei, which requires treatment with a topical allylamine or azole antifungal agent. Physical examination findings are otherwise normal. The 5-cm, well-demarcated, erythematous, annular, scaly plaque involves the entire left eyelid and extends onto the nasal bridge. The mother applied the cream for 2 weeks and noted improvement in the redness initially however, over the next 2 weeks, the lesion persisted and rapidly enlarged. When the rash first appeared 4 weeks earlier, she presented to her pediatrician who prescribed a topical combination nystatin and triamcinolone acetonide cream. If a breast-feeding infant experiences an adverse effect related to a maternally ingested drug, healthcare providers are encouraged to report the adverse effect to the FDA.Case: A 10-year-old girl is brought for evaluation of an itchy, red, enlarging rash on the left eyelid. Consider the benefits of breast-feeding, the risk of potential infant drug exposure, and the risk of an untreated or inadequately treated condition.
#NYSTATIN CREAM FOR ECZEMA SKIN#
Topical nystatin products are not absorbed from intact skin or mucous membranes. However, gastrointestinal absorption of oral nystatin is insignificant therefore, minimal serum and milk concentrations would be expected. It is unknown whether oral nystatin is excreted in human milk. Nystatin should be used during pregnancy only when clearly needed.
However, gastrointestinal absorption of oral nystatin is insignificant and systemic absorption is minimal. It also is not known whether these preparations can cause fetal harm when used during human pregnancy or can affect reproductive capacity. Sulconazole: (Moderate) The combination of sulconazole and nystatin represents duplication of therapy whenever the drugs are used by similar routes and are usually avoided.Īnimal reproduction studies have not been conducted with any oral or topical nystatin preparation. Sertaconazole: (Moderate) The combination of sertaconazole and nystatin represent duplication of therapy whenever the drugs are used by similar route, and is usually avoided. Oxiconazole: (Moderate) The combination of oxiconazole and nystatin represents duplication of therapy whenever the drugs are used by similar routes and are usually avoided. Miconazole Petrolatum Zinc Oxide: (Moderate) The combination of miconazole and nystatin represents duplication of therapy whenever the drugs are used by similar routes and are usually avoided. Miconazole: (Moderate) The combination of miconazole and nystatin represents duplication of therapy whenever the drugs are used by similar routes and are usually avoided. Ketoconazole: (Moderate) The combination of ketoconazole and nystatin represents duplication of therapy whenever the drugs are used by similar routes and are usually avoided. Store between 68 to 77 degrees F, excursions permitted 59 to 86 degrees FĮconazole: (Moderate) The combination of econazole and nystatin represents duplication of therapy whenever the drugs are used by similar routes and are usually avoided. Avoid excessive heat (above 104 degrees F)
Refrigerate (between 36 and 46 degrees F) Store at controlled room temperature (between 68 and 77 degrees F)
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